Low-carb pepperoni pizza chicken bake

This Low-Carb Pepperoni Pizza Chicken Bake features tender chicken breasts topped with pasta sauce, pepperoni, and melted mozzarella. It's a satisfying dish combining classic pizza flavors in a healthier, low-carb format.

21 Apr 2026
Cook time 50 min
Prep time 20 min

Ingredients:

1.67 cup pasta sauce
8 chicken breasts
1 tsp dried oregano
1 tsp garlic powder
1 tbsp olive oil
1 cup mozzarella cheese
2 oz pepperoni
Low-carb pepperoni pizza chicken bake

If you're looking for a delicious and healthy alternative to traditional pizza, this Low-carb Pepperoni Pizza Chicken Bake is an excellent choice. Combining the flavors of classic pizza with the protein-packed goodness of chicken breasts, this dish is both satisfying and nutritious. It’s perfect for those on a low-carb or keto diet, or anyone simply trying to eat healthier without sacrificing taste.

Instructions:

1. Preheat Oven:
- Preheat your oven to 375°F (190°C).
2. Prepare Chicken:
- Pat dry the chicken breasts with paper towels.
- Season the chicken breasts evenly with dried oregano and garlic powder on both sides.
3. Cook Chicken:
- Heat 1 tablespoon of olive oil in a large skillet over medium-high heat.
- Once the oil is hot, add the chicken breasts to the skillet.
- Sear the chicken breasts for about 3-4 minutes on each side until they are golden brown (they do not need to be fully cooked at this stage, as they will finish cooking in the oven).
4. Assemble the Dish:
- Spread 1/3 of the pasta sauce evenly across the bottom of a baking dish.
- Arrange the seared chicken breasts on top of the sauce.
- Pour the remaining pasta sauce over the chicken breasts, ensuring they are all well-covered.
5. Add Toppings:
- Evenly distribute the pepperoni slices.
- Sprinkle the shredded mozzarella cheese evenly over the top of the sauce-covered chicken.
6. Bake:
- Place the baking dish in the preheated oven.
- Bake for 25-30 minutes, or until the chicken is cooked through (internal temperature should reach 165°F or 74°C) and the cheese is bubbly and golden.
7. Serve:
- Remove the dish from the oven and let it rest for a few minutes.
- Serve the Low-Carb Pepperoni Pizza Chicken Bake hot, perhaps alongside a fresh green salad or steamed vegetables for a complete meal.

This Low-carb Pepperoni Pizza Chicken Bake is a delightful way to enjoy all the best parts of pizza without the extra carbs. With tender, juicy chicken breasts topped with savory pasta sauce, a generous layer of melted mozzarella cheese, and crispy pepperoni, it’s sure to become a family favorite. Not only is it quick and simple to prepare, but it also makes for great leftovers.

Low-carb pepperoni pizza chicken bake FAQ:

What should the internal temperature of the chicken be when it's fully cooked?

The internal temperature of the chicken should reach 165°F (74°C) to ensure it is fully cooked and safe to eat.

How long do I need to bake the dish?

Bake the Low-Carb Pepperoni Pizza Chicken Bake for 25-30 minutes in a preheated oven at 375°F (190°C) until the chicken is cooked through and the cheese is bubbly.

Can I use a different type of cheese instead of mozzarella?

Yes, you can substitute mozzarella with other cheeses like provolone or cheddar, but keep in mind that it may alter the flavor and melt characteristics.

What is the best way to store leftovers?

Store any leftovers in an airtight container in the refrigerator for up to 3-4 days. Reheat in the microwave or oven before serving.

Can I use chicken thighs instead of chicken breasts?

Yes, chicken thighs can be used as a substitute for chicken breasts. They may add a richer flavor and remain moist during baking.

Cooking Tips:

- To make the chicken more flavorful, marinate it in olive oil, garlic powder, and oregano for a few hours before cooking.

- For an extra layer of flavor, sear the chicken breasts in a hot pan with olive oil before assembling the bake.

- Use high-quality mozzarella cheese for the best melting and stretch.

- Feel free to add additional low-carb toppings such as olives, bell peppers, or mushrooms.

- Let the dish rest for a few minutes after baking to allow the juices to redistribute evenly.

- Serve with a side of steamed vegetables or a fresh salad to complete the meal.

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Nutrition Facts

8 Servings
Calories 250kcal
Protein 33g
Carbohydrates 5g
Fiber 1.10g
Sugar 3.14g
Fat 11g

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